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MAK3/C14orf35 Rabbit pAb (bs-18638R)  
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產(chǎn)品編號 bs-18638R
英文名稱 MAK3/C14orf35 Rabbit pAb
中文名稱 14號染色體開放閱框35抗體
別    名 C14orf35; Chromosome 14 open reading frame 35; FLJ35355; MAK 3; Mak3p; MGC141884; MGC141885; N acetyltransferase 12(GCN5 related putative); N acetyltransferase 12; N acetyltransferase MAK3 homolog; NAT12; Putative N acetyltransferase.  
研究領(lǐng)域 腫瘤  細胞生物  信號轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 39 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAK3/C14orf35: 251-350/362 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 MAK3 belongs to the acetyltransferase family, MAK3 subfamily. It contains one N-acetyltransferase domain. It is a probable N-acetyltransferase.

Function:
Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate.

Subunit:
Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

Subcellular Location:
Cytoplasmic

Similarity:
Belongs to the acetyltransferase family. MAK3 subfamily.
Contains 1 N-acetyltransferase domain.

SWISS:
Q147X3

Gene ID:
122830

Database links:

Entrez Gene: 122830 Human

Entrez Gene: 70646 Mouse

Entrez Gene: 288108 Rat

SwissProt: Q147X3 Human

SwissProt: Q8CES0 Mouse

Unigene: 165465 Human

Unigene: 275688 Mouse

Unigene: 15205 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (C14orf35) Polyclonal Antibody, Unconjugated (bs-18638R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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