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HUS1B Rabbit pAb (bs-18108R)  
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產(chǎn)品編號 bs-18108R
英文名稱 HUS1B Rabbit pAb
中文名稱 檢查點蛋白HUS1B抗體
別    名 Checkpoint protein HUS1B; hHUS1B; HUS1(S. pombe) checkpoint homolog b; HUS1 Checkpoint Homolog B(S. pombe); MGC126746; MGC126748; RP11 532F6.1.  
研究領域 細胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Rat (predicted: Human,Mouse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 31 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HUS1B: 51-150/278 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008]

Function:
This protein is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the checkpoint protein RAD1 but not with RAD9. Over-expression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.

Similarity:
Belongs to the HUS1 family.

SWISS:
Q8NHY5

Gene ID:
135458

Database links:

Entrez Gene: 135458 Human

Omim: 609713 Human

SwissProt: Q8NHY5 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat adrenal gland); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HUS1B) Polyclonal Antibody, Unconjugated (bs-18108R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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