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TMEFF1 Rabbit pAb (bs-17320R)  
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產(chǎn)品編號(hào) bs-17320R
英文名稱 TMEFF1 Rabbit pAb
中文名稱 TMEFF1蛋白抗體
別    名 Tomoregulin-1 precursor; C9orf2; C9orf3 TMEFF1; C9orf30 TMEFF1; C9orf30 TMEFF1 fusion protein; Cancer/testis antigen family 120 member 1; CT120.1; H 7365; H7365; MSANTD3-TMEFF1 readthrough; TEFF 1; TEFF1; TEFF1_HUMAN; TMEFF 1; Tomoregulin-1; TR 1; TR-1; TR1; Transmembrane protein with EGF like and two follistatin like domains 1; Transmembrane protein with EGF-like and one follistatin-like domain.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TEFF1: 161-260/380 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This locus represents naturally occurring read-through transcription from the neighboring MSANTD3 (Myb/SANT-like DNA-binding domain containing 3) and TMEFF1 (transmembrane protein with EGF-like and two follistatin-like domains 1) genes. The read-through transcript encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Aug 2013]

Function:
May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.

Similarity:
Belongs to the tomoregulin family.
Contains 1 EGF-like domain.
Contains 2 Kazal-like domains.

SWISS:
Q8IYR6

Gene ID:
8577

Database links:

Entrez Gene: 100526694 Human

Entrez Gene: 8577 Human

Entrez Gene: 230157 Mouse

Entrez Gene: 63845 Rat

Omim: 603421 Human

SwissProt: Q8IYR6 Human

SwissProt: Q6PFE7 Mouse

SwissProt: Q9QYV1 Rat

Unigene: 598100 Human

Unigene: 422686 Mouse

Unigene: 162809 Rat



產(chǎn)品圖片
Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-TEFF1 (bs-17320R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 37 kD Observed band size: 37 kD
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