| 產(chǎn)品編號(hào) | bs-16717R |
| 英文名稱 | FOXO6 Rabbit pAb |
| 中文名稱 | 叉頭蛋白O6抗體 |
| 別 名 | Forkhead box protein O6; FOXO6_HUMAN. |
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Specific References (1) | bs-16717R has been referenced in 1 publications.
[IF=5.19] Zhao Tingyi. et al. Metformin alleviates the cognitive impairment induced by benzo[a]pyrene via glucolipid metabolism regulated by FTO/FoxO6 pathway in mice. ENVIRON SCI POLLUT R. 2023 May;:1-13 WB ; Mouse.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 65 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FOXO6: 51-150/492 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Murine Foxo6 is a member of the murine forkhead family of transcription factors. This family consists of over 30 members, the vast majority of which is important in embryonic development. These forkhead transcription factors may play a role in maintenance and survival of developing and adult neurons. Function: Transcriptional activator (By similarity). Subcellular Location: Cytoplasmic and Nuclear. When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors. Post-translational modifications: Phosphorylation of Ser-184 is be important in regulating the transacriptional activity (By similarity). Similarity: Contains 1 fork-head DNA-binding domain. SWISS: A8MYZ6 Gene ID: 100132074 Database links: Entrez Gene: 100132074 Human Entrez Gene: 329934 Mouse Omim: 611457 Human SwissProt: A8MYZ6 Human SwissProt: Q70KY4 Mouse Unigene: 277090 Mouse Unigene: 190858 Rat
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| 產(chǎn)品圖片 |
Sample:
Lung (Mouse) Lysate at 40 ug
Primary: Anti- FOXO6 (bs-16717R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 52 kD
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