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DNAH2 Rabbit pAb (bs-14363R)  
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50ul/1180.00元
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200ul/2800.00元
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產品編號 bs-14363R
英文名稱 DNAH2 Rabbit pAb
中文名稱 軸絲動力蛋白2抗體
別    名 axonemal; Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2; Dnah2; DYH2_HUMAN; Dynein heavy chain 2; Dynein heavy chain domain-containing protein 3.  
研究領域 細胞生物  信號轉導  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Pig,Horse)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 507 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAH2: 3201-3300/4427 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]

Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.

Subcellular Location:
Cytoplasm; cytoskeleton; cilium axoneme.

Tissue Specificity:
Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in lung.

Similarity:
Belongs to the dynein heavy chain family.
Contains 5 TPR repeats.

SWISS:
Q9P225

Gene ID:
146754

Database links:

Entrez Gene: 146754 Human

SwissProt: Q9P225 Human

Unigene: 367649 Human



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