| 產(chǎn)品編號 | bs-13558R |
| 英文名稱 | ZNF93 Rabbit pAb |
| 中文名稱 | 鋅指蛋白93抗體 |
| 別 名 | FLJ12488; HPF34; HTF34; TF34; Zinc finger protein 505; Zinc finger protein 93(HTF34); Zinc finger protein 93; Zinc finger protein HTF34; ZNF505; ZNF93; ZNF93_HUMAN. |
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Specific References (1) | bs-13558R has been referenced in 1 publications.
[IF=0.252] Xiao-Xiao Cui. et al. High expression of ZNF93 promotes proliferation and migration of ovarian cancer cells and relates to poor prognosis. Int J Clin Exp Patho. 2020; 13(5): 944–953 IHC ; Human.
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| 研究領(lǐng)域 | 細胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 71 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZBT24/ZNF45: 521-620/620 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:25274305). Not able to repress expression of all subtypes of L1 elements. Binds to the 5 end of L1PA4, L1PA5 and L1PA6 subtypes, and some L1PA3 subtypes. Does not bind to L1PA7 or older subtypes nor at the most recently evolved L1PA2 and L1Hs. 50% of L1PA3 elements have lost the ZNF93-binding site, explaining why ZNF93 is not able to repress their expression (PubMed:25274305). Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. DISEASE: Expressed early during embryonic development. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 17 C2H2-type zinc fingers. Contains 1 KRAB domain. SWISS: P35789 Gene ID: 81931 Database links: Entrez Gene: 81931 Human Omim: 603975 Human SwissProt: P35789 Human Unigene: 301059 Human Unigene: 723768 Human |
| 產(chǎn)品圖片 |
Sample:
HL-60 (human)cell Lysate at 40 ug
MCF-7 (human)cell Lysate at 40 ug
Primary: Anti-ZNF93 (bs-13558R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 71 kD
Observed band size: 71 kD
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