| 產(chǎn)品編號(hào) | bsm-62379R |
| 英文名稱(chēng) | SMG1 Recombinant Rabbit mAb |
| 中文名稱(chēng) | 絲氨酸/蘇氨酸蛋白激酶Smg1重組兔單抗 |
| 別 名 | 61E3.4; ATX; hSMG1; LIP; smg1. |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Recombinant |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 411 kDa |
| 檢測(cè)分子量 | 410 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human SMG1: 3600-3661 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]-Q. Plays a central role in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating UPF1/RENT1. Recruited by release factors to stalled ribosomes together with SMG8 and SMG9 (forming the SMG1C protein kinase complex), and UPF1 to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex. SWISS: Q96Q15 Gene ID: 23049 |
| 產(chǎn)品圖片 |
Western blot analysis of Saos2 cell lysate. Using SMG1 (bsm-62379R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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