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Niemann Pick C1 Like 1 Recombinant Rabbit mAb (bsm-62028R)  
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產(chǎn)品編號(hào) bsm-62028R
英文名稱 Niemann Pick C1 Like 1 Recombinant Rabbit mAb
中文名稱 鞘磷脂沉積病C1樣蛋白1重組兔單抗
別    名 NPC1 LIKE 1; NPC1L1.  
抗體來(lái)源 Rabbit
克隆類型 Recombinant
克 隆 號(hào)
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:1000-1:2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 149 kDa
檢測(cè)分子量 149
性    狀 Liquid
免 疫 原 A synthesized peptide derived from human NPC1L1: 1300-1359/1359 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存條件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Plays a major role in cholesterol homeostasis.Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte.Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol.Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia.

SWISS:
Q9UHC9

Gene ID:
29881

產(chǎn)品圖片
Western blot analysis of HeLa cell lysate. Using Niemann Pick C1 Like 1 (bsm-62028R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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