| 產(chǎn)品編號(hào) | bsm-61723R |
| 英文名稱(chēng) | NHE1 Recombinant Rabbit mAb |
| 中文名稱(chēng) | 鈉氫通道蛋白重組兔單抗 |
| 別 名 | APNH; APNH1; NHE1; SLC9A1. |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Recombinant |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 91 kDa |
| 檢測(cè)分子量 | 130 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human SLC9A1: 50-100 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Electroneutral Na+ /H+ antiporter that extrudes Na+ in exchange for external protons driven by the inward sodium ion chemical gradient, protecting cells from acidification that occurs from metabolism. SWISS: P19634 Gene ID: 6548 通道蛋白（Channel Protein） 鈉-氫交換蛋白（NHE： Na+/H+ Exchanger）是維持細(xì)胞內(nèi)環(huán)境的主要細(xì)胞膜蛋白質(zhì)之一，它的一個(gè)主要功能是調(diào)節(jié)細(xì)胞內(nèi)pH值，使之保持在生理范圍之內(nèi)。細(xì)胞內(nèi)pH值的變化，直接或間接的影響細(xì)胞的生長(zhǎng)分裂、增殖和分化，也影響細(xì)胞的死亡。 鈉-氫交換蛋白質(zhì)的活性還影響細(xì)胞的移動(dòng)和腫瘤細(xì)胞的轉(zhuǎn)移。 目前主要方向是：研究消化道腫瘤細(xì)胞轉(zhuǎn)移。 |
| 產(chǎn)品圖片 |
Western blot analysis of MOLT4 cell lysate. Using NHE1 (bsm-61723R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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