| 產(chǎn)品編號(hào) | bsm-61716R |
| 英文名稱 | IGFBP2 Recombinant Rabbit mAb |
| 中文名稱 | 胰島素樣生長(zhǎng)因子結(jié)合蛋白2重組兔單抗 |
| 別 名 | BP2; IBP2; IGF BP53; IGFBP2; IGFBP53. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 2D1 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:100-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 35 kDa |
| 檢測(cè)分子量 | 35 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human IGFBP2: 280-325/325 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. SWISS: P18065 Gene ID: 3485 生長(zhǎng)因子和激素（ Growth Factor and Hormones） 胰島素樣生長(zhǎng)因子結(jié)合蛋白-2(IGFBP-2)是IGF/IGFBP家族中的一個(gè)重要成員,在多種疾病尤其是腫瘤中其表達(dá)明顯增高,可能通過調(diào)節(jié)胰島素樣生長(zhǎng)因子(insulin-like growth factor,IGF)發(fā)揮作用，促進(jìn)腫瘤的發(fā)生發(fā)展。 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with IGFBP2 monoclonal antibody, unconjugated (bsm-61716R) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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